10 of the Most Important Diseases With No Licensed Vaccine

Vaccination has been successful at controlling many of the world’s diseases. However, there still remain many infectious diseases for which no licensed (US or EU) vaccine exists. Here I’ve selected 10 of them – arranged in no particular order – which I think are especially important. Click Next to read them > I look forward to hearing your thoughts. Next …

The buzz about Sanaria’s malaria vaccine Phase I results

Early stage clinical testing of Sanaria's intravenous malaria vaccine has shown promise, according to results published in Science. The vaccine, known as PfSPZ, contains attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), was shown to be safe and well tolerated when administered to the 40 adult volunteers. However, it’s not the safety profile that has excited the malaria research community. The vaccine …

Top 3 malaria presentations

Malaria: With so many articles on our blog, it might sometimes be daunting to find just the ones you need.  I've listed below our top 3 presentations from various conferences on the different issues surrounding the malaria vaccine. Advancements in Malaria vaccine production Col. Ockenhouse shared with us his teams very important research malaria vaccines and gave us an outlook …

Climate change in vaccine trials: Moving from a one-size-fits-all to a custom fit in operational delivery

Dr Vigdorth has 30 years of drug development research experience in the clinical setting and pharmaceutical and CRO industries. She has led clinical development programs across a range of therapeutic indications with extensive experience in antibiotic, antiviral, vaccine, and antifungal agents.   Dr Vigdorth's experience has developed from multiple perspectives including working in the clinical investigative site setting, multi- national …

2020 vision for vaccines against HIV, tuberculosis and malaria

Rino Rappuoli, PhD, is Global Head of Vaccines Research at Novartis Vaccines and Diagnostics and is based in Siena, Italy.   In one of his most recent publications in Nature together with Alan Aderem, they discuss their 2020 vision for vaccines against HIV, tuberculosis and malaria.   Acquired immune deficiency syndrome (AIDS), malaria and tuberculosis collectively cause more than five …