Scientists Figure Out Staying Power of HIV-Fighting Enzyme: Enzyme’s double-edged sword may soon be sheathed

SAMHD1 is a human enzyme that depletes cells of their reservoir of DNA building blocks. When supplies of the blocks are low, bits of HIV DNA wreak havoc on immune cells, leaving patients susceptible to other infections. Researchers now understand how SAMHD1 works and may be able to develop a drug to block it. April 30, 2014 Johns Hopkins biochemists …