Regulatory Protein Discovery Key to Malaria Parasite transmission: Potential for sexual-stage vaccine

February 23, 2014 Two teams have independently discovered that a single regulatory protein acts as the master genetic switch that triggers the development of male and female sexual forms (termed gametocytes) of the malaria parasite, solving a long-standing mystery in parasite biology with important implications for human health. The protein, AP2-G, is necessary for activating a set of genes that …