Replikins explains how an analysis of gene structures in the dengue virus led to the development of a vaccine candidate

How a Genetic Analysis of Dengue Led to the Vaccine Candidate

Replikins explains how an analysis of gene structures in the dengue virus led to the development of a vaccine candidate Replikins Ltd, the company that first identified a group of peptides called Replikins, has announced that one of its studies on the genetic structure of the dengue virus has been instrumental in the development of their synthetic dengue vaccine candidate. …

Sanofi’s Dengue Vaccine Produces Moderate results

  The New Dengue Vaccine From Sanofi Shows Promise The virus spread through the day biting Aedes mosquitoes, affects more than one million people a year, threatening about 40% of the worlds population. Sanofi’s candidate vaccine will protect children already infected with the mosquito-borne dengue fever, from a potentially fatal hemorrhagic fever. Evidence suggest that the new dengue fever vaccine protects …

The World’s First, Large-Scale Dengue Vaccine Efficacy Study Successfully Achieved Its Primary Clinical Endpoint

First available data demonstrated a 56% reduction of dengue disease cases in a study of more than 10,000 volunteers from Asia Initial safety data are consistent with the good safety profile observed in previous studies April 28, 2014 Sanofi Pasteur, the vaccines division of Sanofi, today announced that the first of two pivotal Phase III efficacy studies with its dengue …

Researchers Discover New Target for Dengue Virus Vaccine

February 26, 2014 Creating a vaccine that protects people from all four types of dengue virus has frustrated scientists for decades. But researchers at the University of North Carolina have discovered a new target for human antibodies that could hold the key to a vaccine for the world’s most widespread mosquito-borne disease: dengue virus. Using an experimental technique new to …

Download Ebook: The Dengue Vaccine Challenge

  Click here to download this ebook > Dengue fever is a global problem but there isn’t yet a preventative vaccine. In fact, there is currently no specific treatment for dengue, though early detection and access to proper medical care can help lower death rates. Most dengue fever patients suffer through days of raging fever, sweats and a bubbling rash. …

Bring on 2015 – a great year for vaccines

2015 looks like it could be a very good year indeed – although perhaps not so much if you're a mosquito-transmitted parasite. 2015 marks exactly halfway through the Decade of Vaccines, and how better to celebrate this milestone than to potentially revolutionise the control of two burdensome mosquito-transmitted diseases. Firstly, GlaxoSmithKline has announced that it hopes to debut the world's …

Why when vaccine trials fail it is a sad day for global public health

It saddens me to read about failed clinical trials in vaccines for many reasons, but mostly because of the impact these failures might have on the wider global vaccine research and development. With the recent news about Sanofi Pasteur's not as effective phase II trial results for their Dengue Fever vaccine, it just made me think how this will affect …