Challenges in non-clinical testing of innovative immunotherapies /therapeutic vaccines

Dr Emmanuelle Cornali, Head of Business Development, Aurigon Life Sciences joined us at the World Vaccine Congress Lyon 2012 to discuss the challenges for non-clinical assessment for therapeutic vaccines, which include: Efficacy: few relevant animal models high species specificity unconventional PK/PD relationship Safety: difficult modelling of patient population (pediatric, cancer patients) relevance/predictivity of animal data no legal definition -> no …