Research From the John Hopkins Kimmel Cancer Centre Has Shown that Tissue-Damaging Bacteria Has Been Used to Effectively Target Tumours
Research that has taken place at the John Hopkins Kimmel Cancer Centre has used a genetically modified form of the microbe Clostridium novyi to target tumors. The microbe is found in environments that are very low in oxygen, and thus the microbe effectively targets oxygen-starved tumour cells.
The study, published in Science Translational Medicine, showed that injecting the cancer fighting microbe into soft tissue tumors in 16 dogs lead to various positive outcomes. Out of the 16 dogs, three of them recovered from the cancer and their tumours regressed completely, another three showed a 30% reduction in tumour size and another 6 showed a degree of anti-tumor responses.
Trials on humans, however, have not been extensive. The microbe therapy has only been tested on one person so far, with a soft tissue tumour in their abdomen, and the result was that the tumour reduced dramatically in size.
What is promising about this kind of therapy is that preliminary research in rats has showed that the microbe does not attack healthy human cells, but instead only attacks tumour cells.
These kinds of bacterial therapies have been used before to elicit a an immune response against cancer cells.
Read more about it here: Cancer research Shows Bacteria Therapy Effective