Download: Clinical Development of SE36 Malaria Vaccine-

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Earlier this year at the World Vaccine Congress Asia 2013 Congress, Toshihiro Horii, Ph.D RIMD, Osaka University delivered the presentation: Malaria: Innovating prophylactic vaccine pipeline for tropical infectious diseases -Clinical Development of SE36 Malaria Vaccine.

Download this presentation to read about:

  • Structure of SERA5 protein and SE36 recombinant molecule
  • Correlation of anti-SE36 antibody levels with parasitemia in residents from the Solomon Islands
  • Sero-positive rate against N-terminal domain of SERA is very low in younger generations and increases with age
  • Clinical trials of BK-SE36 in Uganda
  • Phase 1b: Trial design
  • Administration site reactions
  • Immunogenicity of BK-SE36
  • Follow-up study
  • Vaccine efficacy
  • Non-Responder to BK-SE36
  • Responder to BK-SE36
  • Changes in antibody titer in responders ( >2 increase of titer by vaccination)
  • Correlation between vaccine response and reinfection
  • Nucleotide diversity of P. falciparum SERA5

Click here to download this presentation

If this interests you then you may also be interested in attending the World Vaccine Congress Asia 2014 event, click here to visit the event website for more information

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