Dry powered foodstuffs like instant drink mixes and powered milk can be made by spray-drying, where an atomised liquid is rapidly dried with hot air to produce a powder. The concept is also not new to the pharmaceutical industry, especially in the manufacture pharmaceuticals such as antibiotics and analgesics.
Now the spray-dry technique can also be applied to vaccine development, where the vaccine is spray-dried with a sugar solution to create solid glass spheres. The microspheres can then be suspended in a non-aqueous liquid or used as a rapidly dissolving powder, and once injected the bodily fluids reactive the vaccine. Such technology is employed by Nova Laboratories’ VitRIS and HydRIS systems (originally developed by Cambridge Biostability).
[Image source: Flickr: Lindsey Turner]