On the second day of the upcoming World Vaccine Congress Asia 2013, Mr. Manoj Kumar will be speaking on the topic "Exploring learnings from the development of the AG129 mouse model of Dengue using suckling mouse brain passages laboratory stocks of DEN viruses". The talk will cover examining the differences in the adaptation of suckling mouse brain stocks of the four DENV serotypes to mosquito and human cell lines, as well as identifying strategies for the rapid development of the AG129 mouse model of DENV2 infection with viremia, increased vascular leak, thrombocytopenia and inflammatory spleen collapse. He will also be reviewing virulence differences among the four DENV serotypes in AG129 mice.
Mr. Manoj Kumar is the Associate research Director of Novel Proteins – Antiviral Therapeutic Proteins Group at Reliance Life Sciences, India. He has also previously held positions including being the Assistant Professor of Research in the Department of Microbiology and Immunology in the University of Illinois and in the Feinberg School of Medicine Northwestern University, as well as being the Research Associate in the Department of Neurology Evanston Northwestern Healthcare Research Institute. Mr. Kumar holds a PhD in Biotechnology from Madurai Kamaraj University, India.