Here is the first in the series of presentations from the expert speakers at the World Vaccine Congress Washington 2013. Subscribe to the Vaccinenation newsletter so you don't miss any >
Technologies for the discovery and development of new vaccines by Dr. Agnete B. Fredriksen, CSO, Vaccibody AS
Dr Fredriksen began by defining the current needs of vaccines:
Â· Need for a new technology giving fast, high, sustainable and broad immune responses
o Few vaccinations
o Low doses
o High safety profile
o Efficacy in challenging settings- like therapeutic cancer vaccines
Â· Interest for a technology tuning the antibody and T cell responses
o Custom design vaccines for each disease's correlate of protection
Â· Isotypes, location
Â· Th1, Th2
Vaccibody AS is working on developing new technolgoyies to meet these needs. In particular, Dr Fredriksen discussed Vaccibodies: flexible, dimeric vaccines able to bind antigen presenting cells 4 Targeting Module Vaccine Module Dimerization Module Ligands binding to Antigen Presenting Cells Hinge and CH3 Domain from IgG Cancer, viral or bacterial antigens.
Why not download the full presentation to discover more about this new technology! Tell us what you think by commenting in the space provided below.